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Initial release: rarelens platform skeleton (AGPL-3.0)
End-to-end variant interpretation platform for rare genetic disease research:
SvelteKit UI, FastAPI + PostgreSQL API, Nextflow/Ensembl VEP pipeline,
LightGBM pathogenicity scoring with MLflow, K8s/ArgoCD/GCP infrastructure.
Public test data only; no clinical claims.
2026-09-11 16:55:35 +01:00

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Makefile

.PHONY: up down migrate test pipeline kind lint
up:
docker compose up -d --build
down:
docker compose down -v
migrate:
docker compose exec api alembic upgrade head
test:
cd api && uv run pytest -q
cd web && npm test
lint:
cd api && uv run ruff check . && uv run mypy app
cd web && npm run check
pipeline:
cd pipeline && nextflow run main.nf -profile docker --vcf ../data/example.vcf.gz --outdir results
kind:
kind create cluster --name rarelens || true
kubectl apply -k infra/k8s/overlays/local