Initial release: rarelens platform skeleton (AGPL-3.0)

End-to-end variant interpretation platform for rare genetic disease research:
SvelteKit UI, FastAPI + PostgreSQL API, Nextflow/Ensembl VEP pipeline,
LightGBM pathogenicity scoring with MLflow, K8s/ArgoCD/GCP infrastructure.
Public test data only; no clinical claims.

api/pyproject.toml

@@ -0,0 +1,28 @@
+[project]
+name = "rarelens-api"
+version = "0.1.0"
+description = "FastAPI backend for rarelens"
+requires-python = ">=3.12"
+dependencies = [
+  "fastapi>=0.115",
+  "uvicorn[standard]>=0.30",
+  "sqlalchemy[asyncio]>=2.0",
+  "asyncpg>=0.29",
+  "alembic>=1.13",
+  "pydantic>=2.8",
+  "pydantic-settings>=2.4",
+  "httpx>=0.27",
+  "mlflow-skinny>=2.16",
+  "lightgbm>=4.5",
+  "pandas>=2.2",
+]
+
+[project.optional-dependencies]
+dev = ["pytest", "pytest-asyncio", "ruff", "mypy", "aiosqlite"]
+
+[tool.ruff]
+line-length = 100
+target-version = "py312"
+
+[tool.pytest.ini_options]
+asyncio_mode = "auto"