v2 methylation control QC (WIP): simurg methyl qc|convert-manifest (MET-001..018)
Methylation CSV manifest reader (MET-002/003), raw M/U assembly with bead masking (MET-005), pOOBAH detection p-values, noob background correction, linear/nonlinear dye bias, beta and M-values (MET-010..012), the 21 methylation control metrics (MET-006, bs-conv red-bg set option), per-sample ctrl/cgs tables, summary tsv/xlsx/html with the detection histogram and a beta PCA, pcs.tsv.gz, controls_raw/controls_qc.tsv; methylation datasets load in qc report (MET-014); qc controls --array-type methylation; minfi-style Sentrix_ID/Sentrix_Position sheet keys. Vendor EPIC manifests carry a 5th field on some control lines: >= 4 fields accepted. Runs on the public minfiDataEPIC set (3 x NA12878).
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@@ -51,6 +51,20 @@ canonical:
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bs conversion i u3: bs1_U3
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bs conversion i u4: bs1_U4
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bs conversion i u5: bs1_U5
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bs conversion i-c1: bs1_C1
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bs conversion i-c2: bs1_C2
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bs conversion i-c3: bs1_C3
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bs conversion i-c4: bs1_C4
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bs conversion i-c5: bs1_C5
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bs conversion i-c6: bs1_C6
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bs conversion i-u1: bs1_U1
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bs conversion i-u2: bs1_U2
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bs conversion i-u3: bs1_U3
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bs conversion i-u4: bs1_U4
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bs conversion i-u5: bs1_U5
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bs conversion i-u6: bs1_U6
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bs conversion i c6: bs1_C6
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bs conversion i u6: bs1_U6
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bs conversion ii-1: bs2_1
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bs conversion ii-2: bs2_2
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bs conversion ii-3: bs2_3
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