CN: per-probe heterozygous BAF spread from the batch reference; --mosaic-prior/--switch-distance; Pi memory guard
scripts/pi_run.sh runs heavy jobs in their own process group and stops them when MemAvailable drops below a floor (Raspberry Pi OS boots with cgroup_disable=memory, so a systemd MemoryMax cap is not available); a 360-sample genotype run with cohort QC had exhausted memory and the OOM killer took down the desktop session. Co-Authored-By: Claude Opus 5.5 <[email protected]> Claude-Session: https://claude.ai/code/session_01814GKVzZVL3FuF3DeiZXhv
This commit is contained in:
1 parent
07a4caff51
commit
46be8f7ffd
5 files changed
+80
-16
No files matched your search
@@ -733,6 +733,12 @@ def cn_call_cmd(
|
||||
svlen_mode: Annotated[str, typer.Option("--svlen-mode", help="signed|positive")] = "signed",
|
||||
mask_bed: Annotated[Path | None, typer.Option("--mask-bed", help="Mask BED (default: built-in).")] = None,
|
||||
no_bgzip: Annotated[bool, typer.Option("--no-bgzip", help="Plain VCF (cn annotate then refuses it).")] = False,
|
||||
mosaic_prior: Annotated[
|
||||
float, typer.Option("--mosaic-prior", help="Advanced: mosaic states' switch mass.")
|
||||
] = 0.004,
|
||||
switch_distance: Annotated[
|
||||
float, typer.Option("--switch-distance", help="Advanced: HMM switch distance D (bp).")
|
||||
] = 5e8,
|
||||
threads: ThreadsOpt = 0,
|
||||
force: ForceOpt = False,
|
||||
log_json: LogJson = False,
|
||||
@@ -761,7 +767,8 @@ def cn_call_cmd(
|
||||
opts = CnCallOptions(
|
||||
out=out, bpm=bpm, model=model, gtcs=gtcs, summary=summary, fasta=fasta, thresholds=th, smoothing=smoothing,
|
||||
cn_cap=cn_cap, gc_correct=gc_correct, unknown_sex_policy=unknown_sex_policy, gt_mode=gt_mode,
|
||||
svlen_mode=svlen_mode, mask_bed=mask_bed, bgzip=not no_bgzip, threads=threads, force=force,
|
||||
svlen_mode=svlen_mode, mask_bed=mask_bed, bgzip=not no_bgzip, mosaic_prior=mosaic_prior,
|
||||
switch_d=switch_distance, threads=threads, force=force,
|
||||
argv=sys.argv[1:],
|
||||
) # fmt: skip
|
||||
run_guarded(rep, lambda: run_cn_call(opts, rep))
|
||||
|
||||
Reference in new issue
Block a user