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branding: SimurgArray brand kit (mark, wordmark, lockups, icons, templates, guide)
ci #89
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2026-09-30 06:52:06 +00:00
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blog: featured images (1200x630, ~90 KB) and a branding brief
ci #88
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2026-09-30 06:22:35 +00:00
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blog: five posts on SimurgArray (why, alternatives, impact, public release plan, usage and branding)
ci #87
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ef42a33efc
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2026-09-30 05:25:25 +00:00
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Release 2.0.0: v2 modules (ArrayTrain, CN/LOH, PGx, methylation QC)
ci #86
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v2.0.0
2026-09-30 05:25:22 +00:00
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Release 2.0.0: v2 modules (ArrayTrain, CN/LOH, PGx, methylation QC)
ci #85
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2026-09-30 05:24:59 +00:00
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test_p6_vcf: stream the gtc2vcf oracle output (OUT-012)
ci #84
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2026-09-30 00:25:48 +00:00
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CN: final full-cohort cloud validation (GSE165845, CYTO-041/042 defaults)
ci #83
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6cbac9ee06
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2026-09-29 22:04:32 +00:00
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ArrayTrain: BIC-selected unbounded θ mixtures + HWE-guided labelling
ci #82
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ccf7f4f156
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2026-09-29 21:40:36 +00:00
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train: loop variable typing (mypy)
ci #81
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2026-09-29 18:54:39 +00:00
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ArrayTrain (plan §12): simurg train — EGT cluster files from a cohort's GTCs
ci #80
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2026-09-29 18:54:11 +00:00
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PGx validation on GSE165845: WGS-derived star truth, 2-fold masks, array-resolvable concordance
ci #79
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2026-09-29 18:00:52 +00:00
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CHANGELOG: v2 CN/LOH/mosaicism and pharmacogenomics
ci #78
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2026-09-29 16:16:27 +00:00
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docs: user guide sections for CN/LOH/mosaicism and pharmacogenomics
ci #77
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2026-09-29 16:16:00 +00:00
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tests: PGx demo oracle tests — definition sanity (PGX-023), limitations (PGX-009), determinism (PGX-029), JSON/TSV (PGX-028)
ci #76
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2026-09-29 16:15:24 +00:00
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pgx_cn: PFB as float64 for the BAF evidence (mypy)
ci #75
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2026-09-29 16:12:07 +00:00
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PGx CN: scan-date batch warning (PCN-006), CN-consistent BAF evidence (PCN-010, --bafs-in-cn),
ci #74
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2026-09-29 16:11:47 +00:00
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PGx: ClinPGx variant-based genes (PGX-008) and --guideline dpwg (PGX-025)
ci #73
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2026-09-29 16:01:53 +00:00
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PGx: PharmVar genes (CYP1A2, CYP2A6, CYP2A13, CYP2C8, CYP3A4), CYP2A6 *4 from CN (PGX-001/006)
ci #72
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2026-09-29 15:50:44 +00:00
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PGx: CYP2D6 structures from sub-region CN — *68+*4, *36+*10, *13 (PGX-013/018)
ci #71
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2026-09-29 15:30:14 +00:00
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PGx: all CPIC gene kinds — G6PD, variant-based, HLA tags, *0 CN genes (PGX-006/007/021)
ci #70
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2026-09-29 15:24:51 +00:00
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PGx: full call detail (PGX-016..020, 027/028, 031), pgx coverage (PGX-009/035), full HGVS
ci #69
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2026-09-29 15:16:53 +00:00
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PGx phenotypes: pgx phenotype|annotate (PGX-024..028, CLI-034)
ci #68
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2026-09-29 15:03:41 +00:00
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derive_masks: keep pysam's downloaded tabix indexes in data/pgx/cache, not the working directory
ci #67
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2026-09-29 15:00:44 +00:00
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PGx star alleles: pgx star-allele call (PGX-011..021), probe masks vs 1000G, GeT-RM validation (K-029)
ci #66
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2026-09-29 13:08:22 +00:00
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PGx DB: pgx db build from CPIC (PGX-001..005, IN-053, CLI-035)
ci #65
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2026-09-29 12:25:09 +00:00
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PGx CN: pgx copy-number train|call (CLI-031/032, PCN-001..017, IN-050), region BED v1, demo identities (K-028)
ci #64
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2026-09-29 12:16:33 +00:00
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V2 CN: CYTO-042 results (precision up, mosaic calls halved); pi_run reports process memory without page cache
ci #63
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2026-09-29 11:20:56 +00:00
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cn build-model: compute the per-probe LRR spread in column chunks (peak memory hit the 5 GB cap on 120 GSA arrays)
ci #62
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2026-09-29 11:11:55 +00:00
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CN: per-probe LRR noise from the batch reference (CYTO-042), --probe-lrr-sd/--no-probe-lrr-sd
ci #61
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2026-09-29 11:00:25 +00:00
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cn_validate_truth: sensitivity by carrier frequency (rare < 5 % is the primary metric, K-027)
ci #60
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2026-09-29 10:58:15 +00:00
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