Files
rarelens/api/tests/test_model_loading.py
Kemal Yaylali 11fb6b3d73 fix: overhaul the platform skeleton, add a serverless deployment track
An end-to-end audit found the repo could not build, test or run as shipped. This
fixes every finding, then adds a Cloud Run track so the demo costs about £1/month
idle instead of ~£150.

CI (red on its first run)
- api: setuptools could not build the package (flat layout with app/ and alembic/)
- web: missing @types/node; `vitest run` exited 1 with no test files
- pipeline: the stub run needed a gitignored VCF, and no process had a stub block
- ruff pinned, mypy configured, DB tests on real Postgres (pgserver locally, service in CI)

ML serving (scores were meaningless)
- the registered model now carries its own feature engineering and returns predict_proba,
  so serving sends raw columns and cannot drift from training
- resolve by registry alias (stages are deprecated in MLflow 3) and record the real
  version; re-scoring upserts instead of failing on the unique constraint
- ClinVar labels parsed from VEP's lowercase terms

Pipeline
- exact ref/alt recovered from a CHROM_POS_REF_ALT VCF ID; loading is idempotent
- job status reaches running/failed/succeeded, so the UI stops polling dead jobs
- DATABASE_URL travels in the environment or a Nextflow secret, never on a command line
- VEP cache and plugins staged as inputs; the gcp profile runs tasks on Google Batch

Deployment
- the API serves /api (matching the ingress); the web app reads its API URL at runtime
- migrations run in an init container under a Postgres advisory lock
- terraform: custom VPC shared with Batch, private Cloud SQL, API enablement, Workload
  Identity bindings, Secret Manager, deletion protection
- serverless track, now the default: Cloud Run services scaling to zero, a Cloud Run job
  for the Nextflow driver, and Neon or Cloud SQL behind one DATABASE_URL secret. GKE and
  Argo remain, behind -var deploy_kubernetes=true. See docs/cloud.md.

Correctness and security
- 409 on duplicate sample names, 422 on bad paging, natural chromosome ordering, wider
  VEP text columns, enum dropped on downgrade, the sample's assembly actually used
- vcf_uri restricted to gs:// objects or files under the data root, blocking option injection
- CORS restricted to configured origins; `make down` no longer deletes volumes

Data
- docs/data.md records the peer-reviewed, openly licensed sources (GIAB HG002, ClinVar,
  gnomAD) with citations and an honest evaluation plan; `make data` fetches a chr22 slice

Verified: api 50 tests, ml 18, loader 16, web 12; ruff, mypy, svelte-check, terraform
validate and both kustomize overlays clean.
2026-09-12 07:21:11 +01:00

48 lines
1.7 KiB
Python

"""A model artifact URI (gs://...) lets the API score without an MLflow server running."""
# Imported eagerly: mlflow loads .pyfunc lazily, so patching it by name can hit the proxy.
import mlflow.pyfunc
import pytest
from app.config import settings
from app.services import scoring
@pytest.fixture(autouse=True)
def clear_cache() -> None:
scoring._models.clear()
def no_registry(**kwargs: object) -> None:
pytest.fail("the registry must not be contacted when MODEL_URI is set")
def test_model_uri_skips_the_registry(monkeypatch: pytest.MonkeyPatch) -> None:
monkeypatch.setattr(settings, "model_uri", "gs://bucket/models/pathogenicity/3")
monkeypatch.setattr(scoring, "MlflowClient", no_registry)
monkeypatch.setattr(mlflow.pyfunc, "load_model", lambda uri: f"model@{uri}")
model, version = scoring.load_model()
assert model == "model@gs://bucket/models/pathogenicity/3"
assert version == "3"
def test_model_uri_without_a_version_segment_still_labels_the_prediction(
monkeypatch: pytest.MonkeyPatch,
) -> None:
monkeypatch.setattr(settings, "model_uri", "gs://bucket/models/pathogenicity/")
monkeypatch.setattr(scoring, "MlflowClient", no_registry)
monkeypatch.setattr(mlflow.pyfunc, "load_model", lambda uri: "model")
assert scoring.load_model()[1] == "pathogenicity"
def test_model_uri_is_loaded_once(monkeypatch: pytest.MonkeyPatch) -> None:
monkeypatch.setattr(settings, "model_uri", "gs://bucket/models/pathogenicity/3")
monkeypatch.setattr(scoring, "MlflowClient", no_registry)
calls: list[str] = []
monkeypatch.setattr(mlflow.pyfunc, "load_model", lambda uri: calls.append(uri) or "model")
scoring.load_model()
scoring.load_model()
assert len(calls) == 1