import uuid

import pytest
from factories import seed_job
from httpx import AsyncClient


@pytest.mark.parametrize(
    "paging", [{"limit": 0}, {"limit": -1}, {"limit": 501}, {"offset": -1}]
)
async def test_out_of_range_paging_is_422_not_500(client: AsyncClient, paging: dict) -> None:
    r = await client.get("/api/variants", params={"job_id": str(uuid.uuid4()), **paging})
    assert r.status_code == 422


async def positions(client: AsyncClient, job_id: uuid.UUID) -> list[tuple[str, int, str]]:
    r = await client.get("/api/variants", params={"job_id": str(job_id)})
    assert r.status_code == 200, r.text
    return [(v["chrom"], v["pos"], v["alt"]) for v in r.json()["items"]]


@pytest.mark.usefixtures("db")
async def test_chromosomes_sort_naturally(client: AsyncClient) -> None:
    job_id = await seed_job([{"chrom": c} for c in ["10", "MT", "2", "X", "chr3", "1", "Y"]])
    assert [c for c, _, _ in await positions(client, job_id)] == [
        "1", "2", "chr3", "10", "X", "Y", "MT",
    ]


@pytest.mark.usefixtures("db")
async def test_same_position_keeps_insertion_order_across_pages(client: AsyncClient) -> None:
    # Split multiallelics share chrom/pos; without a tiebreak, pages can repeat or skip rows.
    job_id = await seed_job([{"pos": 5, "alt": a} for a in "CGT"])
    assert [a for _, _, a in await positions(client, job_id)] == ["C", "G", "T"]


@pytest.mark.usefixtures("db")
async def test_long_vep_strings_are_stored(client: AsyncClient) -> None:
    clin_sig = ",".join(["conflicting_classifications_of_pathogenicity"] * 8)
    consequence = (
        "splice_region_variant&splice_polypyrimidine_tract_variant&intron_variant"
        "&NMD_transcript_variant&non_coding_transcript_variant"
    )
    job_id = await seed_job([{"clinvar_sig": clin_sig, "consequence": consequence}])
    [v] = (await client.get("/api/variants", params={"job_id": str(job_id)})).json()["items"]
    assert (v["clinvar_sig"], v["consequence"]) == (clin_sig, consequence)