Initial release: rarelens platform skeleton (AGPL-3.0)
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End-to-end variant interpretation platform for rare genetic disease research: SvelteKit UI, FastAPI + PostgreSQL API, Nextflow/Ensembl VEP pipeline, LightGBM pathogenicity scoring with MLflow, K8s/ArgoCD/GCP infrastructure. Public test data only; no clinical claims.
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apiVersion: kustomize.config.k8s.io/v1beta1
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kind: Kustomization
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resources: [../../base]
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images:
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- { name: rarelens/api, newName: europe-west2-docker.pkg.dev/PROJECT/rarelens/api, newTag: latest }
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- { name: rarelens/web, newName: europe-west2-docker.pkg.dev/PROJECT/rarelens/web, newTag: latest }
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patches:
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- target: { kind: ServiceAccount, name: rarelens-api }
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patch: |
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- op: add
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path: /metadata/annotations
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value: { iam.gke.io/gcp-service-account: [email protected] }
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- target: { kind: Deployment, name: api }
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patch: |
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- op: add
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path: /spec/template/spec/containers/-
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value:
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name: cloud-sql-proxy
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image: gcr.io/cloud-sql-connectors/cloud-sql-proxy:2.13.0
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args: ["--structured-logs", "--port=5432", "PROJECT:europe-west2:rarelens-pg"]
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securityContext: { runAsNonRoot: true }
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apiVersion: kustomize.config.k8s.io/v1beta1
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kind: Kustomization
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resources: [../../base, postgres.yaml]
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images:
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- { name: rarelens/api, newName: rarelens-api, newTag: dev }
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- { name: rarelens/web, newName: rarelens-web, newTag: dev }
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secretGenerator:
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- name: api-secrets
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literals: [DATABASE_URL=postgresql+asyncpg://rarelens:rarelens@postgres:5432/rarelens]
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apiVersion: apps/v1
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kind: Deployment
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metadata: { name: postgres }
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spec:
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selector: { matchLabels: { app: postgres } }
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template:
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metadata: { labels: { app: postgres } }
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spec:
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containers:
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- name: postgres
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image: postgres:16-alpine
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env:
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- { name: POSTGRES_USER, value: rarelens }
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- { name: POSTGRES_PASSWORD, value: rarelens }
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- { name: POSTGRES_DB, value: rarelens }
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---
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apiVersion: v1
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kind: Service
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metadata: { name: postgres }
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spec: { selector: { app: postgres }, ports: [{ port: 5432 }] }
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