Initial release: rarelens platform skeleton (AGPL-3.0)
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End-to-end variant interpretation platform for rare genetic disease research:
SvelteKit UI, FastAPI + PostgreSQL API, Nextflow/Ensembl VEP pipeline,
LightGBM pathogenicity scoring with MLflow, K8s/ArgoCD/GCP infrastructure.
Public test data only; no clinical claims.
This commit is contained in:
2026-09-11 16:55:35 +01:00
commit 5463f489a3
74 changed files with 4597 additions and 0 deletions
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apiVersion: apps/v1
kind: Deployment
metadata: { name: api }
spec:
replicas: 2
selector: { matchLabels: { app: api } }
template:
metadata: { labels: { app: api } }
spec:
serviceAccountName: rarelens-api
containers:
- name: api
image: rarelens/api
ports: [{ containerPort: 8000 }]
envFrom: [{ secretRef: { name: api-secrets } }]
readinessProbe: { httpGet: { path: /health, port: 8000 }, periodSeconds: 5 }
resources: { requests: { cpu: 250m, memory: 512Mi }, limits: { cpu: "1", memory: 1Gi } }
---
apiVersion: v1
kind: Service
metadata: { name: api }
spec: { selector: { app: api }, ports: [{ port: 80, targetPort: 8000 }] }
---
apiVersion: v1
kind: ServiceAccount
metadata: { name: rarelens-api }
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apiVersion: networking.k8s.io/v1
kind: Ingress
metadata: { name: rarelens }
spec:
rules:
- http:
paths:
- { path: /api, pathType: Prefix, backend: { service: { name: api, port: { number: 80 } } } }
- { path: /, pathType: Prefix, backend: { service: { name: web, port: { number: 80 } } } }
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apiVersion: kustomize.config.k8s.io/v1beta1
kind: Kustomization
namespace: rarelens
resources: [namespace.yaml, api.yaml, web.yaml, ingress.yaml]
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apiVersion: v1
kind: Namespace
metadata: { name: rarelens }
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apiVersion: apps/v1
kind: Deployment
metadata: { name: web }
spec:
replicas: 2
selector: { matchLabels: { app: web } }
template:
metadata: { labels: { app: web } }
spec:
containers:
- name: web
image: rarelens/web
ports: [{ containerPort: 3000 }]
env: [{ name: PUBLIC_API_URL, value: /api }]
resources: { requests: { cpu: 100m, memory: 128Mi }, limits: { cpu: 500m, memory: 256Mi } }
---
apiVersion: v1
kind: Service
metadata: { name: web }
spec: { selector: { app: web }, ports: [{ port: 80, targetPort: 3000 }] }