kemalandClaude Opus 5.5 1c73f3954b V2 CN validation: Pi tuning rounds, CYTO-041 effect, common-CNV sensitivity limit (K-027) ...

Co-Authored-By: Claude Opus 5.5 <[email protected]>
Claude-Session: https://claude.ai/code/session_01814GKVzZVL3FuF3DeiZXhv

2026-09-29 11:11:14 +01:00

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P1_omni2141_summary.json

P1 validated on 1000 Genomes Omni2.5 (2141 vendor GTCs + IDATs)

2026-09-27 20:22:35 +01:00

P1.md

P1 validated on 1000 Genomes Omni2.5 (2141 vendor GTCs + IDATs)

2026-09-27 20:22:35 +01:00

P2_omni2141_summary.json

P2 validated on 2141 vendor GTCs (1000 Genomes Omni2.5)

2026-09-27 22:19:28 +01:00

P2.md

P2 validated on 2141 vendor GTCs (1000 Genomes Omni2.5)

2026-09-27 22:19:28 +01:00

P3_omni2141_summary.json

P3 validated: normalization bit-identical on 2141 vendor GTCs

2026-09-27 23:41:43 +01:00

P3.md

P3 validated: normalization bit-identical on 2141 vendor GTCs

2026-09-27 23:41:43 +01:00

P4_omni2141_summary.json

P4 validated on 2141 vendor GTCs; legacy AutoCall 1.6.2 preset

2026-09-28 01:21:49 +01:00

P4_preset_omni2141_summary.json

P5 validated on 2141 1000G samples; control-metric fixes (K-021)

2026-09-28 10:25:32 +01:00

P4.md

P4 validated on 2141 vendor GTCs; legacy AutoCall 1.6.2 preset

2026-09-28 01:21:49 +01:00

P5_omni2141_summary.json

P5 validated on 2141 1000G samples; control-metric fixes (K-021)

2026-09-28 10:25:32 +01:00

P5.md

P5 validated on 2141 1000G samples; control-metric fixes (K-021)

2026-09-28 10:25:32 +01:00

P6_gsa36_vs_gtc2vcf.json

P6 validated against GTCtoVCF too: zero unexplained genotype differences

2026-09-28 13:20:44 +01:00

P6_gsa36_vs_gtctovcf.json

P6 validated against GTCtoVCF too: zero unexplained genotype differences

2026-09-28 13:20:44 +01:00

P6.md

P6 complete: optional VCF fields, SNV+indel merging, auxiliary MNV loci, PLINK 2 .pgen

2026-09-28 14:29:42 +01:00

P7.md

P7: differential-testing harness (simurg compare) and nightly run on the Pi

2026-09-28 17:00:37 +01:00

P8_gse165845_summary.json

P8 complete: scientific validation on GSE165845 vs NYGC 30x and GIAB HG001

2026-09-28 19:47:34 +01:00

P8.md

P8 complete: scientific validation on GSE165845 vs NYGC 30x and GIAB HG001

2026-09-28 19:47:34 +01:00

P9_identity_360.json

P9 complete: compiled kernels validated (byte-identical, 78-80 GSA samples/min/core), scaling report

2026-09-28 22:32:48 +01:00

P9_scaling_gp3.json

P9 complete: compiled kernels validated (byte-identical, 78-80 GSA samples/min/core), scaling report

2026-09-28 22:32:48 +01:00

P9_scaling_ramdisk.json

P9 complete: compiled kernels validated (byte-identical, 78-80 GSA samples/min/core), scaling report

2026-09-28 22:32:48 +01:00

P9.md

P9 complete: compiled kernels validated (byte-identical, 78-80 GSA samples/min/core), scaling report

2026-09-28 22:32:48 +01:00

P10.md

P10 complete: packaging verified on fresh x86_64 and aarch64 VMs

2026-09-28 23:53:59 +01:00

V2_cn_gse165845_q10.json

v2 CN: real-data validation vs NYGC 30x SVs (interim), noise gate on normalised LRR (K-027)

2026-09-29 07:42:06 +01:00

V2_cn_gse165845_q20.json

v2 CN: real-data validation vs NYGC 30x SVs (interim), noise gate on normalised LRR (K-027)

2026-09-29 07:42:06 +01:00

V2_cn_synthetic_gsa36.json

v2 CN: synthetic implant evaluation (CYTO-022); reference GTC discovery follows symlinks

2026-09-29 01:30:07 +01:00

V2_cn.md

V2 CN validation: Pi tuning rounds, CYTO-041 effect, common-CNV sensitivity limit (K-027)

2026-09-29 11:11:14 +01:00

V2_methylation_vs_sesame.json

v2 methylation QC validated on minfiDataEPIC and against sesame (K-026)

2026-09-29 00:41:54 +01:00

V2_methylation.md

v2 methylation QC validated on minfiDataEPIC and against sesame (K-026)

2026-09-29 00:41:54 +01:00