# Phase P0/P1 validation report Date: 2026-09-27 · Machine: Raspberry Pi 5 (aarch64, 4 cores, 8 GB) · Python 3.13, NumPy 2.2. Commands: `pytest tests/unit` (every CI run), `pytest tests/oracle -m "not slow"` and `-m slow` (needs `scripts/fetch_data.sh p0`, `scripts/bootstrap_refs.sh`, `scripts/make_oracle_gtcs.sh`). ## Scope delivered | Plan §18 P1 item | Module | Status | |---|---|---| | Little-endian binary + .NET string codec | `formats/binutil.py` | done | | IDAT v3 reader (gzip, metadata, RunInfo → ISO date, encrypted detection) | `formats/idat.py` | done | | BPM reader (v3–5, locus entries v4/6/7/8, norm-bin rule incl. mod-256 wrap) | `formats/bpm.py` | done | | CSV manifest reader + BPM↔CSV consistency (IN-042) | `formats/csv_manifest.py` | done | | EGT reader (data-block variants, count cross-check) | `formats/egt.py` | done | | GTC v3–v5 reader and writer (layout-preserving) | `formats/gtc.py` | done | | Sample sheet (IN-001 … IN-014) | `formats/samplesheet.py` | done | | IDAT discovery, pairing, duplicates, input-set rule (IN-020 … IN-022, CLI-006) | `formats/discovery.py` | done | | Message catalogue, exit codes, JSON logging, rate limiting | `core/errors.py`, `core/log.py` | done | | Atomic writes, overwrite policy, run manifest | `core/atomic.py`, `core/provenance.py` | done (used from P4 on) | | `simurg version`, `simurg inspect [--json]` | `cli/main.py` | done | | Synthetic IDAT/BPM/EGT writers for tests | `synth/files.py` | done | ## Acceptance results (plan §18 P1 gate) | Criterion | Data | Result | |---|---|---| | GTC fields equal to BeadArrayFiles (23 fields incl. raw X/Y, genotypes, scores, BAF, LRR, base calls, sample stats, percentiles, 48 normalization transforms) | 18 GSA v4 GTCs from gtc2vcf `idat2gtc` (preset: Array Analysis CLI) | **EXACT, 18/18** | | GTC read → write byte-identical | same 18 files; synthetic v3/v5 incl. non-canonical layouts; 25 random property cases | **EXACT** | | BPM equal to BeadArrayFiles (names, SNP, Chr, MapInfo, AddressA, assay type, normalization lookups, RefStrand, manifest name, control config) | GSA v4 PGx BPM (683 054 loci) | **EXACT** | | EGT equal to BeadArrayFiles (N, θ/R mean/SD ×3, intensity threshold, GenTrain score, cluster separation, address) | GSA v4 (683 054 records) and GDA v1 (1 904 599 records), ~5 000 evenly spaced records each | **EXACT** | | BPM ↔ CSV consistency (IN-042: names, counts, Chr, MapInfo, SNP, AddressA/B) | GSA v4 | **0 differences** | | All IDATs parse and pair; Red/Grn address sets equal; same address set on every chip | 72 GSA IDATs (36 samples, 2 chips) | **pass** | | Manifest addresses present in IDATs | GSA v4 | **100 %** | | Bioconductor fixtures: 381 079 / 622 399 addresses (plain + gzip); 2 encrypted files → `E_IDAT_ENCRYPTED` | IlluminaDataTestFiles 1.50.0 | **pass** | | Malformed inputs never raise uncaught exceptions (truncation, bad magic, bad TOC offsets, bad string lengths, duplicates) | synthetic matrix (EDGE-002, EDGE-004) | **pass** | | Sample-sheet matrix EDGE-007 (27 cases) incl. 10 000 rows < 2 s (PERF-007) | synthetic | **pass** | | Locale independence of `inspect --json` (C, tr_TR, de_DE) | synthetic | **pass** | ## Performance on the Pi (single thread, pure Python/NumPy) | Operation | Time | Peak RSS | |---|---|---| | IDAT read (734 656 addresses) | 3 ms | – | | GTC read (683 054 loci) | 34 ms | – | | EGT read GSA / GDA | 2.2 s / 6.1 s | – | | CSV manifest read GSA | 12.5 s | 713 MB | | BPM read GSA | 17.8 s | 665 MB | BPM/CSV parsing is the only slow step; it is a one-off per run and moves to Rust in P9 (or is cached). ## Not yet covered (needs the larger machine / later phases) - GEO sweep of 254 genotyping IDAT series and the 1000 Genomes Omni2.5 set (plan §18 P1 wording) — P1 is validated on P0 data only; rerun `tests/oracle` after `scripts/fetch_data.sh p1`. - GTCs written by vendor software (only gtc2vcf-written GTCs are available locally); the 1000 Genomes Broad set contains vendor GTCs. - IN-027 (IDAT ↔ manifest coverage gate) is P2; the coverage computation is already exercised by a test.