Commit Graph
2 Commits
Author SHA1 Message Date
kemal d2c99d6673 P8 cloud task: stream NYGC VCFs through bcftools instead of downloading
The download-only phase (EBI ~15 MB/s) left the CPU idle long enough for the
idle alarm to terminate the first run. Streams are now cut to the manifest
positions (±100 bp) and the 120 individuals while genotyping runs.
2026-09-28 19:06:36 +01:00
kemal 8cc1e52f69 P8: GSE165845 validation scripts (prepare, §16.5 metrics) and cloud task
scripts/p8/prepare.py lays out the 360 GEO IDATs under their header barcode/position;
scripts/p8/validate_p8.py computes concordance, NRD, no-call rate, per-class and per-MAF
sensitivity/specificity/precision/F1 vs NYGC 30x and GIAB HG001, replicate concordance,
systematic/allele-swap site errors, per-chip batch table and duplicate detection.
Cloud userdata can skip the Omni2.5 archive (OMNI=0).
2026-09-28 17:43:31 +01:00